| Product Name | GluR-?2 Polyclonal Antibody |
| Cat Number | HR1AP6751 |
| Source | Rabbit |
| Applications | WB,IF,ELISA |
| Species Reactivity | Human,Mouse,Rat |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Observed Band | 113 |
| Gene ID | GRID2 |
| Alternative Name | GRID2; GLURD2; Glutamate receptor delta-2 subunit; GluR delta-2 subunit |
| Background | glutamate ionotropic receptor delta type subunit 2(GRID2) Homo sapiens The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this |
| Type | polyclonal |