| Product Name | COX1 Polyclonal Antibody |
| Cat Number | HR1AP2269 |
| Source | Rabbit |
| Applications | WB |
| Species Reactivity | Human |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. |
| Observed Band | 70 |
| Gene ID | PTGS1 |
| Alternative Name | PTGS1; COX1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1 |
| Background | prostaglandin-endoperoxide synthase 1(PTGS1) Homo sapiens This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], |
| Type | polyclonal |