| Product Name | MYBPC3 Polyclonal Antibody |
| Cat Number | HR1AP7415 |
| Source | Rabbit |
| Applications | IHC-p,ELISA |
| Species Reactivity | Human |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Gene ID | MYBPC3 |
| Alternative Name | MYBPC3; Myosin-binding protein C; cardiac-type; Cardiac MyBP-C; C-protein, cardiac muscle isoform |
| Background | myosin binding protein C, cardiac(MYBPC3) Homo sapiens MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008], |
| Type | polyclonal |