| Product Name | Dynactin 2 Polyclonal Antibody |
| Cat Number | HR1AP3318 |
| Source | Rabbit |
| Applications | WB,IHC-p,ELISA |
| Species Reactivity | Human,Mouse,Rat |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Observed Band | 50 |
| Gene ID | DCTN2 |
| Alternative Name | DCTN2; DCTN50; Dynactin subunit 2; 50 kDa dynein-associated polypeptide; Dynactin complex 50 kDa subunit; DCTN-50; p50 dynamitin |
| Background | dynactin subunit 2(DCTN2) Homo sapiens This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012], |
| Type | polyclonal |