| Product Name | DSCR 1 Polyclonal Antibody |
| Cat Number | HR1AP3315 |
| Source | Rabbit |
| Applications | WB,ELISA |
| Species Reactivity | Human,Mouse,Rat |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Observed Band | 22 |
| Gene ID | RCAN1 |
| Alternative Name | RCAN1; ADAPT78; CSP1; DSC1; DSCR1; Calcipressin-1; Adapt78; Down syndrome critical region protein 1; Myocyte-enriched calcineurin-interacting protein 1; MCIP1; Regulator of calcineurin 1 |
| Background | regulator of calcineurin 1(RCAN1) Homo sapiens The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013], |
| Type | polyclonal |