| Product Name | SEMA4A Polyclonal Antibody |
| Cat Number | HR1AP4529 |
| Source | Rabbit |
| Applications | WB,IHC-p,IF,ELISA |
| Species Reactivity | Human,Mouse,Rat,Monkey |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Observed Band | 84 |
| Gene ID | SEMA4A |
| Alternative Name | SEMA4A; SEMAB; SEMB; Semaphorin-4A; Semaphorin-B; Sema B |
| Background | semaphorin 4A(SEMA4A) Homo sapiens This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identif |
| Type | polyclonal |