FURIN Polyclonal Antibody


FURIN Polyclonal Antibody

Cat No.:HR1AP12443
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Alternative Name:

Antibodies Type: polyclonal



Product Details

Product Name FURIN Polyclonal Antibody
Cat NumberHR1AP12443
SourceRabbit
ApplicationsWB,ELISA
Species Reactivity Human,Rat,Mouse
Storage -20°C/1 year
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration 1 mg/ml
Observed Band 87
Gene ID FURIN FUR PACE PCSK3
Background furin, paired basic amino acid cleaving enzyme(FURIN) Homo sapiens This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix m
Type polyclonal

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