SLAF7 Polyclonal Antibody


SLAF7 Polyclonal Antibody

Cat No.:HR1AP11978
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Antibodies Type: polyclonal



Product Details

Product Name SLAF7 Polyclonal Antibody
Cat NumberHR1AP11978
SourceRabbit
ApplicationsWB,ELISA
Species Reactivity Human,Mouse
Storage -20°C/1 year
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration 1 mg/ml
Observed Band 36
Gene ID SLAMF7 CS1 UNQ576/PRO1138
Background function:Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro).,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,tissue specificity:Expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level tha isoform 1.,
Type polyclonal

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