VPS4B Polyclonal Antibody


VPS4B Polyclonal Antibody

Cat No.:HR1AP11572
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Alternative Name:

Antibodies Type: polyclonal



Product Details

Product Name VPS4B Polyclonal Antibody
Cat NumberHR1AP11572
SourceRabbit
ApplicationsWB,ELISA
Species Reactivity Human,Mouse
Storage -20°C/1 year
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration 1 mg/ml
Observed Band 48
Gene ID VPS4B SKD1 VPS42 MIG1
Background vacuolar protein sorting 4 homolog B(VPS4B) Homo sapiens The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008],
Type polyclonal

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