| Background | function:Promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM:Phosphorylated by TPK II. Poor substrate for GSK3.,similarity:Belongs to the TPPP family.,subunit:May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with GSK3.,tissue specificity:Widely expressed., |
