| Product Name | GRK2 (Phospho-Ser685) Antibody |
| Cat Number | HR1AP9995 |
| Source | Rabbit |
| Applications | WB,ELISA |
| Species Reactivity | Human,Mouse,Rat |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Observed Band | 80 |
| Gene ID | ADRBK1 BARK BARK1 GRK2 |
| Alternative Name | Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2) |
| Background | G protein-coupled receptor kinase 2(GRK2) Homo sapiens The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008], |
| Type | polyclonal |