| Product Name | STK36 Polyclonal Antibody |
| Cat Number | HR1AP6654 |
| Source | Rabbit |
| Applications | WB,IHC-p,ELISA |
| Species Reactivity | Human,Mouse |
| Storage | -20°C/1 year |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Observed Band | 170 |
| Gene ID | STK36 |
| Alternative Name | STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog |
| Background | serine/threonine kinase 36(STK36) Homo sapiens This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011], |
| Type | polyclonal |